{"id":7714718,"date":"2025-11-26T00:20:56","date_gmt":"2025-11-26T00:20:56","guid":{"rendered":"https:\/\/orionhealth.com\/?p=7714718"},"modified":"2026-01-29T19:36:18","modified_gmt":"2026-01-29T19:36:18","slug":"evaluating-ai-in-healthcare-building-safety-fairness-and-trust","status":"publish","type":"post","link":"https:\/\/orionhealth.com\/global\/blog\/evaluating-ai-in-healthcare-building-safety-fairness-and-trust\/","title":{"rendered":"Can you trust your AI? Evaluating healthcare AI before deployment."},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">AI has immense potential to transform healthcare, enhancing diagnostics, optimising workflows, and personalising treatment. Yet the OECD\u2019s 2024 report <em>AI in Health: Huge Potential, Huge Risks,<\/em> warns that poorly governed AI can amplify inequities, compromise patient safety, and erode public trust. Responsible evaluation is therefore a leadership imperative, not a technical afterthought.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Defining purpose and risk: the first step in responsible AI<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Healthcare leaders must first establish the intended purpose, risk level, and value claims of any AI tool.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to NICE\u2019s <em>Evidence Standards Framework for Digital Health Technologies<\/em>, classification into Tiers A\u2013C determines the required level of scrutiny. Tools that diagnose, treat, or guide clinical management fall under Tier C, requiring high standards of safety, performance, and cost-effectiveness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the scoping stage, evaluators should engage early with developers and regulators to confirm whether the AI qualifies as a medical device, what approvals (such as UKCA marking) apply, and what validation data are required. This early alignment helps avoid costly redesigns later in the deployment cycle.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Learning from the NHS: Building an evaluation framework<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The NHS AI Lab\u2019s <em>AI in Health and Care Award<\/em> programme offers a tested model for independent assessment. Its framework evaluates AI across eight domains:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Safety<\/li>\n\n\n\n<li>Accuracy<\/li>\n\n\n\n<li>Effectiveness<\/li>\n\n\n\n<li>Value<\/li>\n\n\n\n<li>Fit with sites<\/li>\n\n\n\n<li>Implementation<\/li>\n\n\n\n<li>Scalability<\/li>\n\n\n\n<li>Sustainability<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This approach allows both technical validation and real-world feasibility testing, ensuring AI solutions are practical and safe for frontline use.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/orionhealth.com\/wp-content\/uploads\/Vital-Signs-A-Proposed-Phased-Approach-to-Responsible-AI-Development-and-Deployment.svg\" alt=\"\" class=\"wp-image-7714719\"\/><figcaption class=\"wp-element-caption\"><strong>A Proposed Phased Approach to Responsible AI Development and Deployment<\/strong><br>Source: Makhni et al., Mayo Clinic Proceedings: Digital Health (2025)<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">What Makes an Effective AI Evaluation?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Key lessons from the NHS and global literature include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mixed-methods evaluation:<\/strong> Combine quantitative clinical data with qualitative feedback from clinicians and patients to capture usability and impact.<\/li>\n\n\n\n<li><strong>Flexible study designs:<\/strong> Use quasi-experimental or pragmatic trial designs that adapt to evolving technologies.<\/li>\n\n\n\n<li><strong>Data governance clarity:<\/strong> Define data-sharing responsibilities, anonymisation, and post-market monitoring from the outset.<\/li>\n\n\n\n<li><strong>Longer evaluation timelines:<\/strong> Allow \u2018bedding-in\u2019 periods so staff can adjust workflows before outcomes are measured.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">These steps ensure that evaluations move beyond proof of concept into real-world impact.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ensuring Safety, Fairness, and Explainability<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AI systems must be safe, fair, and explainable. Frameworks such as the <em>Blueprint for Trustworthy AI<\/em> and <em>Singapore\u2019s AI Governance Guidelines<\/em> emphasise transparency across the entire lifecycle, from data sourcing and algorithm training to deployment and monitoring.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Leaders should implement continuous validation processes to detect model drift and retrain algorithms with updated datasets. Bias monitoring can include health equity audits and analysis by patient demographics to identify disparities.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Equally critical is explainability. Tools like <em>model cards<\/em> or <em>Unique AI Identifiers<\/em> help document a system\u2019s purpose, data lineage, and limitations, fostering accountability across developers, clinicians, and healthcare organisations.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/orionhealth.com\/wp-content\/uploads\/Vital-signs-Strategies-to-improve-development-and-dissemination-of-AI-tools-in-health-and-health-care.svg\" alt=\"\" class=\"wp-image-7714720\"\/><figcaption class=\"wp-element-caption\"><strong>Strategies to Improve Development and Dissemination of AI Tools in Health and Healthcare<\/strong><br>Source: <em>Angus et al., JAMA (2025)<\/em><\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Measuring Value: Beyond Cost and Efficiency<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AI adoption should be grounded in evidence of measurable value. NICE requires proof not only of clinical outcomes but also cost-effectiveness and budget impact.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evaluators should:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Map current care pathways.<\/li>\n\n\n\n<li>Identify how AI changes those pathways.<\/li>\n\n\n\n<li>Measure both direct costs (licensing, infrastructure, training) and indirect effects (efficiency gains, error reduction).<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">According to OECD guidance, value should encompass trust, equity, and workforce sustainability, in addition to financial metrics.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The Need for Continuous Oversight<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Post-deployment evaluation is just as crucial as pre-deployment testing. Leaders should:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Establish AI safety reporting systems similar to those used in NHS clinical incident processes.<\/li>\n\n\n\n<li>Implement independent assurance mechanisms, like the <em>Coalition for Health AI\u2019s<\/em> proposed \u201cAI Labs\u201d, to audit datasets and manage certification renewals.<\/li>\n\n\n\n<li>Invest in ongoing training, equipping clinicians to interpret AI outputs responsibly and maintain human oversight in automated environments.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Transparency in Reporting: The Path to Accountability<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Transparent reporting ensures trust and reproducibility in AI-driven healthcare research. Several frameworks now support this goal:<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/orionhealth.com\/wp-content\/uploads\/Vital-Signs-Examples-of-AI-related-reporting-guidelines.svg\" alt=\"\" class=\"wp-image-7714721\"\/><figcaption class=\"wp-element-caption\"><strong>Examples of AI-Related Reporting Guidelines<\/strong><br>Source: <em>Flanagin et al., JAMA (2024)<\/em><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>CONSORT-AI and SPIRIT-AI for clinical trial design and protocols.<\/li>\n\n\n\n<li>MI-CLAIM, CLAIM, and MINIMAR for clinical AI modelling and imaging.<\/li>\n\n\n\n<li>DECIDE-AI for early-stage live evaluations.<\/li>\n\n\n\n<li>STARD-AI, TRIPOD-AI, and CHART (in development) for diagnostic and chatbot studies.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">These frameworks are helping healthcare move towards a shared standard of AI transparency and reliability.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">A continuous cycle of trust<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Evaluating AI is not a one-off exercise; it\u2019s an iterative process:<br><strong>Plan \u2192 Test \u2192 Deploy \u2192 Monitor \u2192 Refine<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The goal is not to slow innovation but to ensure that AI delivers equitable, safe, and explainable improvements in care.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Before deploying AI in healthcare, leaders should always ask:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Is it safe, effective, and fair?<\/li>\n\n\n\n<li>Is it transparent, explainable, and accountable?<\/li>\n\n\n\n<li>Will it sustainably improve outcomes for patients and staff?<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">When frameworks such as those pioneered by NHS England and NICE are rigorously applied, AI can enhance, not endanger, the human dimension of healthcare.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Authored by\u00a0<a href=\"https:\/\/orionhealth.com\/uk\/author-tom-varghese\/\" target=\"_blank\" rel=\"noreferrer noopener\">Tom Varghese<\/a>, Global Product Marketing &amp; Growth Manager at Orion Health.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Resources<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>AI in Health and Care Award. Planning and Implementing Real-World Artificial Intelligence (AI) Evaluations: Lessons from the AI in Health and Care Award. NHS England, 2024<\/li>\n\n\n\n<li>Coalition for Health AI (CHAI). Blueprint for Trustworthy AI: Implementation Guidance and Assurance for Healthcare. Version 1.0. April 2023<\/li>\n\n\n\n<li>Flanagin, Annette, Romain Pirracchio, Rohan Khera, Michael Berkwits, Yulin Hswen, and Kirsten Bibbins-Domingo. \u201cReporting Use of AI in Research and Scholarly Publication\u2014JAMA Network Guidance.\u201d JAMA 331, no. 13 (April 2, 2024): 1096\u20131098<\/li>\n\n\n\n<li>Labkoff, Steven, Bilikis Oladimeji, Joseph Kannry, et al. \u201cToward a Responsible Future: Recommendations for AI-Enabled Clinical Decision Support.\u201d Journal of the American Medical Informatics Association 31, no. 11 (2024): 2730\u20132739<\/li>\n\n\n\n<li>Makhni, Sonya, Jose Rico, Paul Cerrato, et al. \u201cA Comprehensive Approach to Responsible AI Development and Deployment.\u201d Mayo Clinic Proceedings: Digital Health 3, no. 4 (2025): 100294.\u00a0<\/li>\n\n\n\n<li>Ministry of Health (Singapore). Artificial Intelligence in Healthcare Guidelines (AIHGle). Published October 2021<\/li>\n\n\n\n<li>National Institute for Health and Care Excellence (NICE). Evidence Standards Framework for Digital Health Technologies. Updated August 2022<\/li>\n\n\n\n<li>Nature Medicine Editorial Board. \u201cSetting Guidelines to Report the Use of AI in Clinical Trials.\u201d Nature Medicine 26, no. 9 (September 2020): 1311<\/li>\n\n\n\n<li>Organisation for Economic Co-operation and Development (OECD). AI in Health: Huge Potential, Huge Risks. Paris: OECD Publishing, 2024<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>AI has immense potential to transform healthcare, enhancing diagnostics, optimising workflows, and personalising treatment. Yet the OECD\u2019s 2024 report AI in Health: Huge Potential, Huge Risks, warns that poorly governed AI can amplify inequities, compromise patient safety, and erode public trust. Responsible evaluation is therefore a leadership imperative, not a technical afterthought. Defining purpose and [&hellip;]<\/p>\n","protected":false},"author":47,"featured_media":7714722,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[1],"tags":[274],"region":[25,26,23,24,27,28],"class_list":["post-7714718","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-ai-in-healthcare","region-au","region-ca","region-global","region-nz","region-uk","region-us"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Evaluating AI in Healthcare: Building Safety, Fairness and Trust - Orion Health<\/title>\n<meta name=\"description\" content=\"How healthcare leaders can evaluate AI responsibly, ensuring safety, fairness, and transparency from design to deployment.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/orionhealth.com\/global\/blog\/evaluating-ai-in-healthcare-building-safety-fairness-and-trust\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaluating AI in Healthcare: Building Safety, Fairness and Trust - Orion Health\" \/>\n<meta property=\"og:description\" content=\"How healthcare leaders can evaluate AI responsibly, ensuring safety, fairness, and transparency from design to deployment.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/orionhealth.com\/global\/blog\/evaluating-ai-in-healthcare-building-safety-fairness-and-trust\/\" \/>\n<meta property=\"og:site_name\" content=\"Orion Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/orionhealth\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-26T00:20:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-29T19:36:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/orionhealth.com\/wp-content\/uploads\/Vargheses-Vitals-vol-35.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1180\" \/>\n\t<meta property=\"og:image:height\" content=\"886\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Tom Varghese\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@OrionHealth\" \/>\n<meta name=\"twitter:site\" content=\"@OrionHealth\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tom Varghese\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/orionhealth.com\\\/blog\\\/evaluating-ai-in-healthcare-building-safety-fairness-and-trust\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/orionhealth.com\\\/blog\\\/evaluating-ai-in-healthcare-building-safety-fairness-and-trust\\\/\"},\"author\":{\"name\":\"Tom Varghese\",\"@id\":\"https:\\\/\\\/orionhealth.com\\\/uk\\\/#\\\/schema\\\/person\\\/3b2a5fdf2f01464f0f04e54f8db998f9\"},\"headline\":\"Can you trust your AI? 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