The platform for unified health data and actionable insights, powering smarter Health Information Exchanges.

Transform fragmented health data into a unified, longitudinal view, bringing all the right information together so you can identify at-risk patients sooner, guide care with confidence, and scale proven AI insights across your entire health system.   

The Smart AI evolution in Health Information Exchanges

For more than 30 years, our Amadeus Health Information Exchange system has powered national health systems and Health Information Exchanges, connecting thousands of providers and securely unifying billions of clinical records into a single, longitudinal patient view. Built with clinicians, it helps teams work more efficiently, improve safety, and reduce burnout.

Now, with the AI SMARTSuite, Amadeus evolves into an intelligence-enabled platform. Embedded directly into workflows, clinically validated AI unlocks real-time insights, predictive capabilities, and intelligent clinical workflows. Enhancing decision-making and personalising care without disrupting existing systems.

Start with a proven interoperability backbone, ready to scale when you are.

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Why it matters: An intelligent, connected backbone for healthcare

What if the problem is not the data; it's how it’s being used? Amadeus AI provides clarity into a patient's full record while delivering interoperability at scale.

Enable a longitundinal patient record

Unify patient data from across social and health care into one longitudinal record. Proven at national scale, FHIR-native, API-friendly, and built to grow with your system.

Connect systems without barriers

Integrate legacy platforms, modern apps, and new data sources seamlessly. Event-aware architecture ensures secure, real-time data sharing.

Coordinated, standardised care delivery

Digitise workflows, track referrals end-to-end, and embed guidelines with decision support to improve coordination, standardise care, and reduce variation while maintaining visibility across providers.

The right information at the right time

Surface context-relevant patient information, labs, imaging, medications, encounters, when and where it’s needed, reducing duplication and improving decision-making.

Start with what works. Scale to what’s next.

Design a platform that fits your system, your priorities, and your pace.

The Trusted Foundation

Built on a robust clinical data repository (CDR) and FHIR-based architecture, it delivers a trusted, technical foundation for interoperability, connecting disparate systems into a single source of truth. This supports clinical workflows, reduces duplication, and improves patient safety.

Add capabilities as your needs evolve

Extend the platform with configurable modules for a clinical portal, care coordination, cohort management, population health, and analytics, supporting referrals, care pathways, and clinical workflows to streamline outcomes without added complexity.

Unlock intelligence across the platform

SMARTSuite enhances the core with DARWEN™ AI, a clinically validated, patented AI engine built for healthcare. Embedded in clinical workflows, SMARTSearch, SMARTSummary, and SMARTIdentify surface what matters, enable earlier risk detection, and support faster, more confident decisions.

Start with what works. Scale to what’s next.

Design a platform that fits your system, your priorities, and your pace.

Amadeus Solution Layer Diagram Draft-Core
The Trusted foundation

Unify fragmented data into a real-time, longitudinal patient record through a clinician-first shared care record and clinical portal. Built for interoperability, it connects systems into a single source of truth, supporting clinical workflows, reducing duplication, and improving safety.

Amadeus Solution Layer Diagram Draft-Mod
Add capabilities as your needs evolve

Extend the platform with configurable modules for care coordination, cohort management, population health, and analytics, supporting referrals, care pathways, and clinical workflows to streamline outcomes without added complexity.

Amadeus Solution Layer Diagram Draft-SS
Unlock intelligence across the platform

SMARTSuite enhances the core with DARWEN™ AI, a clinically validated, patented AI engine built for healthcare. Embedded in clinical workflows, SMARTSearch, SMARTSummary, and SMARTIdentify surface what matters, enable earlier risk detection, and support faster, more confident decisions.

Key Features

Combine capabilities to create a unified patient data platform that connects systems, empowers teams, and drives better outcomes.

Optimised clinician experience

A clinician-first patient record platform, shaped by 30 years of frontline insight, with clear navigation, AI guided workflows, mobile access, and a unified view of patient information.

User analytics and benefits realisation

Track system utilisation and user behaviour through intuitive dashboards that demonstrate adoption and realised value.

Clinical Intelligence at the point of care

Smart capabilities powered by DARWEN AI that identify high-risk patients, deliver AI-driven clinical summaries from years of data, and surface actionable insights to support decisions at the point of care.

National network ready

A trusted integration backbone with bi-directional HL7v2, FHIR, terminology services, and secure exchange gateways built for regional, and national interoperability at scale.

Seamless integration without replacement

Integrate existing systems into Amadeus workflows to create a seamless experience across current and new capabilities, without the need for replacement.

Cohort-Based workflow​

Modular tools for tracking cohorts and coordinating care across chronic conditions, transitional care, and community services. Configurable workflows, shared task visibility, and automated follow-ups help ensure no patient is missed, extending core platform capabilities as an add-on.

Powered by HEALWELL AI

AI built in, not bolted on

Amadeus AI isn’t your typical electronic health record system with AI slapped on top; it’s powered end-to-end by DARWENTM AI, a patented AI engine specifically designed and tuned to solve healthcare challenges.

While others retrofit general-purpose models, Amadeus AI delivers native, modular intelligence directly into clinical workflows; streamlining decisions, reducing burden, and surfacing what matters most.

At its core, Amadeus AI will include:

  • SmartSearch – Instant insight discovery with natural language search across structured and unstructured records
  • SmartSummary – Clear, clinical summaries that cut complexity
  • SmartIdentify – Unified clinical and social data for risk detection and cohort insights

With explainable, workflow-aligned insights and Orion Health’s proven healthcare interoperability, Amadeus AI will transform complexity into intelligent, coordinated care, enabling prevention, prediction, and action at scale.

What Amadeus AI means for you

Modular, flexible, and built to fit your people, your priorities, and your system.

For Clinicians

For Health System Leaders

For Technology and Delivery Partners

For Public Health Leaders

For Clinicians

Clinicians spend too much time navigating fragmented systems to find the information they need. Amadeus brings data together into a single, longitudinal patient view, while SMARTSuite enhances it with AI-powered summaries that surface the most relevant labs, imaging, and clinical notes instantly.

From triage to care planning and transitions, clinicians can review results, track trends, and take the next best action within a single workflow. Whether coordinating care, sharing insights, or initiating referrals, everything is connected, context-aware, and designed for speed, clarity, and safer decisions.

For Health System Leaders

Operational efficiency and clinical quality shouldn’t be at odds. With Amadeus AI, health systems get an interoperable, standards-based Health Information Exchange platform that unifies siloed data and augments decision making at every level. 

Executives gain visibility across populations, service lines, and performance metrics. AI powered insights support smarter resourcing, reduced duplication, and measurable improvement in outcomes, all while reducing cost and risk. 

Whether you’re scaling services, modernising infrastructure, or meeting national targets, Amadeus AI helps you lead with clarity, confidence, and control.  

For Technology and Delivery Partners

Adopting AI at scale shouldn’t mean starting from scratch. Built to slot straight into complex health IT environments, Amadeus AI combines enterprise-grade security with seamless interoperability. 

It supports FHIR R4, HL7 v2, CDA, and is TEFCA-ready. Making integration with existing EHRs, HIEs, and third-party applications frictionless. With proven connectivity to Epic, Cerner, and Allscripts, deployment is fast, and disruption is minimal. 

Backed by HIPAA, ISO, SOC 2, and HITRUST certifications, Amadeus AI keeps data secure across cloud, hybrid, or on-prem environments. It scales from local networks to national infrastructure without compromising performance or compliance. 

Whether supporting digital front doors, clinical pathways, or decision tools, Amadeus AI gives partners flexible, future ready AI. Proven, pluggable, and built for what’s next. 

For Public Health Leaders

Rising demand and delayed interventions are stretching public health systems thin. Amadeus AI equips agencies and policymakers with the predictive insight they need to stay ahead of the curve. 

From chronic disease modelling to demand forecasting and digital twins, the platform reveals population-level trends, identifies risk early, and supports targeted programs that deliver better patient care and improved health outcomes.

Amadeus AI helps turn nationwide medical data into an actionable strategy that enhances prevention and proactive planning for healthcare providers and government leaders.

Amadeus in action

See how leading healthcare organisations are transforming data exhange, care coordination, and outcome.

13.9 millionunique patient records safely and securely housed

Malaffi, Abu Dhabi’s state-wide Health Information Exchange, is powered by Orion Health’s core Amadeus HIE platform and securely connects over 2,400 facilities and 47,000 users.

By unifying patient data across the emirate, it improves safety, reduces duplication, and streamlines care coordination across healthcare providers.

The result? 45 million unique patient records safely housed, enabling better outcomes for patients and health care providers alike.

10 minutesto feel confident using the system

Alberta’s EHR initiative, powered by Amadeus, breaks down data silos. It gives clinicians secure, real-time access to critical patient information across the care continuum. Disparate systems were unified into a single patient view. This includes demographics, histories, diagnostics, and lab results. The interface is intuitive and requires minimal training.

The modular, web-based design improves accuracy and reduces delays. It delivers a consistent clinician experience. It also preserves existing systems and supports seamless future upgrades.

Frequently
Asked Questions

Absolutely. You don’t need to start with AI to see value. Amadeus is a platform that grows with you, whether you begin with the core Amadeus platform or layer in AI capabilities over time. If your HIE data isn’t AI-ready today, that’s okay. We’ll work with you to standardise, connect, and enrich it so you’re ready when the time comes.

In the meantime, the core Amadeus platform improves your clinicians’ workflows by consolidating patient data into a single, clear view, streamlining referrals, and enhancing care coordination. You’ll see immediate value now, while building a strong, future-ready foundation for AI-driven insights when you’re ready to take that next step.

Dive deeper in our blog on getting your data AI ready 

Amadeus builds on decades of proven global HIE delivery, supporting large-scale health systems worldwide. It’s designed for real-world complexity, interoperable by design, with proven integrations across major EHRs like Epic, Cerner, and Allscripts, and support for standards including HL7, FHIR, and CDA.

At its core, Amadeus is a modern, modular health information exchange platform that unifies fragmented data into a single, longitudinal patient view, improving access, usability, and care coordination across the continuum today.

On top of this foundation, Amadeus introduces embedded AI through the SMARTSuite, powered by the clinically validated DARWEN AI engine. This isn’t bolt-on functionality; its intelligence built directly into clinical workflows, surfacing real-time insights, summaries, and predictive recommendations without disrupting care delivery.

The result is a platform that delivers immediate, proven value now, while enabling health systems to seamlessly evolve into AI-driven care when they’re ready.

Amadeus is designed to fit seamlessly into complex health IT environments — whether you’re starting with the core Amadeus platform, extending capabilities with SMARTSuite, or adopting the full Amadeus AI offering.

It supports HL7 v2, FHIR R4, CDA, and is TEFCA-ready, ensuring full compatibility with US interoperability standards. The platform has proven integrations with major EHR vendors like Epic, Cerner, and Allscripts, enabling fast deployment with minimal workflow disruption.

With enterprise-grade certifications including HIPAA, SOC 2, ISO, and HITRUST, Amadeus can be deployed confidently across cloud, on-premises, or hybrid environments.

Yes. Amadeus is backed by HIPAA, SOC 2, ISO, and HITRUST certifications. Whether deployed in cloud, hybrid, or on premises environments, it maintains enterprise grade security while supporting interoperability and scalability across local, regional, and national infrastructures.

Amadeus AI delivers measurable ROI across clinical, operational, and financial outcomes:

  • Reduced duplication and cost by unifying siloed data into a single patient record
  • Faster decision-making with tools like SmartSummary and SmartSearch surfacing key insights instantly
  • Lower operational overhead through standards-based interoperability and streamlined integration
  • Improved patient outcomes via earlier intervention and better care coordination
  • Built-in compliance with TEFCA, CMS 2025, and HIPAA to support secure, scalable growth

Proven at scale, organisations like Malaffi (Abu Dhabi) and Alberta Health (Canada) have unified millions of records, reduced duplication, and achieved rapid clinician adoption.

As you scale into Amadeus AI with SMARTSuite, transform fragmented data into real-time, and unlock actionable insights within existing workflows. Powered by HEALWELL AI’s clinically validated DARWEN™ engine, it enables faster decisions, simplified patient histories, and earlier identification of at-risk patients, driving greater efficiency and outcomes over time.

Yes. Amadeus AI is a modular and flexible platform designed to adapt to the unique needs of different health systems, hospitals, and partners. You can start with core capabilities such as the Clinical Portal or interoperability backbone, and add modules like Care Coordination, Amadeus Insights, or SMARTSuite as your requirements evolve. 

Because it’s standards-based and API-friendly, Amadeus AI integrates smoothly with existing EHRs, HIEs, and third-party applications. Whether you’re a local health network or a national infrastructure, the platform scales with you — ensuring you only invest in what you need, when you need it. 

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