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The platform for unified health data and actionable insights, powering smarter Health Information Exchanges

Transform fragmented health data into a unified, longitudinal view, bringing all the right information together so you can identify at-risk patients sooner, guide care with confidence, and scale proven AI insights across your entire health system.   

The Smart AI evolution in Health Information Exchanges

For more than 30 years, our Amadeus Health Information Exchange system has been connecting thousands of providers, powering national health systems, securely exchanging billions of clinical records, and serving over 150 million patients across 15 countries. Built in collaboration with clinicians, it unites rich data from across the continuum of care into a single view, helping teams work more efficiently, improve safety, and reduce burnout. 

Now, with HEALWELL AI, we’re taking that trusted foundation to the next level. Amadeus AI embeds advanced, clinically validated intelligence directly into the HIE. Streamlining clinical workflows, predicting outcomes, and personalising care without disrupting existing systems. It is next generation interoperability with intelligence built in.   

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Why it matters: An intelligent, connected backbone for healthcare

Modern healthcare has outpaced traditional records. Amadeus AI gives you clarity, prevention, and interoperability at scale.

Enable a single, connected patient record

Unify data from across health and social care into one longitudinal record. Proven at national scale, FHIR-native, API-friendly, and built to grow with your system.

Connect systems without barriers

Integrate legacy platforms, modern apps, and new data sources without disruption. Event-aware architecture ensures secure, real-time data sharing.

Deliver the right information at the right time

Surface context-relevant data, labs, imaging, medications, encounters, when and where it’s needed, reducing duplication and improving decision-making.

Streamline care coordination

Digitise workflows and track referrals end-to-end, giving all providers visibility of responsibilities, status, and outcomes to keep patients moving smoothly through the system.

Improve consistency and safety of care

Embed guidelines, decision support, and workflow prompts into the care record to standardise processes, improve adherence, and reduce variation.

Drive population-level insight and action

Surface real-time, multi-source data to identify at-risk cohorts, measure outcomes, and target interventions, enabling a shift from reactive to proactive care.

Key features

Combine capabilities to create a unified solution that connects systems, empowers teams, and drives better outcomes.

Optimised clinician experience

A clinician-first patient record platform, shaped by 30 years of frontline insight, with clear navigation, AI guided workflows, mobile access, and a unified view of patient data.

National network ready

A trusted integration backbone with bi-directional HL7v2 and FHIR, terminology services, and secure exchange gateways built for local, regional, and national interoperability at scale.

Population and user analytics

Dashboards that track system use, user behaviour, and care access, enabling performance measurement against VBC models and CMS quality metrics.

Clinical Intelligence at the point of care

Smart capabilities powered by DARWEN AI that identify high-risk patients, deliver AI-driven clinical summaries from years of data, and surface actionable insights to support decisions at the point of care.

Cohort-Based workflow​

Modular tools for cohort tracking, care planning, and task management supporting chronic conditions, transitional care, and community services. Configurable workflows and shared task visibility help teams automate follow-up and ensure no patient is missed.

Powered by HEALWELL AI

AI built in, not bolted on

Amadeus AI isn’t your typical electronic health record system with AI slapped on top; it’s powered end-to-end by DARWENTM AI, a patented AI engine specifically designed and tuned to solve healthcare challenges.

While others retrofit general-purpose models, Amadeus AI delivers native, modular intelligence directly into clinical workflows; streamlining decisions, reducing burden, and surfacing what matters most.

At its core, Amadeus AI will include:

  • SmartSearch – Instant insight discovery with natural language search across structured and unstructured records
  • SmartSummary – Clear, clinical summaries that cut complexity
  • SmartIdentify – Unified clinical and social data for risk detection and cohort insights

With explainable, workflow-aligned insights and Orion Health’s proven interoperability, Amadeus AI will transform complexity into intelligent, coordinated care, enabling prevention, prediction, and action at scale.

What Amadeus AI means for you

Modular, flexible, and built to fit your people, your priorities, and your system.

For Clinicians

For Health System Leaders

For Technology and Delivery Partners

For Public Health Leaders

For Clinicians

Clinicians lose valuable time hunting for patient information across fragmented systems. Amadeus AI SMARTSuite will turn your HIE into an intelligent, daily-use tool, delivering AI-powered summaries that surface the most relevant labs, imaging, and clinical notes—instantly.

With Amadeus AI, you spend less time searching and more time with patients. From triaging to care planning and transitions, SMARTSuite will help clinicians stay in the zone, review results, track clinical trends, and take the next best action without leaving their workflow. Whether it’s sharing insights, coordinating care, or initiating a referral, everything is connected, context-aware, and streamlined for speed and safety.

For Health System Leaders

Operational efficiency and clinical quality shouldn’t be at odds. With Amadeus AI, health systems get an interoperable, standards-based platform that unifies siloed data and augments decision making at every level. 

Executives gain visibility across populations, service lines, and performance metrics. AI powered insights support smarter resourcing, reduced duplication, and measurable improvement in outcomes, all while reducing cost and risk. 

Whether you’re scaling services, modernising infrastructure, or meeting national targets, Amadeus AI helps you lead with clarity, confidence, and control. 
 

For Technology and Delivery Partners

Adopting AI at scale shouldn’t mean starting from scratch. Built to slot straight into complex health IT environments, Amadeus AI combines enterprise-grade security with seamless interoperability. 

It supports FHIR R4, HL7 v2, CDA, and is TEFCA-ready. Making integration with existing EHRs, HIEs, and third-party applications frictionless. With proven connectivity to Epic, Cerner, and Allscripts, deployment is fast, and disruption is minimal. 

Backed by HIPAA, ISO, SOC 2, and HITRUST certifications, Amadeus AI keeps data secure across cloud, hybrid, or on-prem environments. It scales from local networks to national infrastructure without compromising performance or compliance. 

Whether supporting digital front doors, clinical pathways, or decision tools, Amadeus AI gives partners flexible, future ready AI. Proven, pluggable, and built for what’s next. 

For Public Health Leaders

Rising demand and delayed interventions are stretching public health systems thin. Amadeus AI equips agencies and policymakers with the predictive insight they need to stay ahead of the curve. 

From chronic disease modelling to demand forecasting and digital twins, the platform reveals population-level trends, identifies risk early, and supports targeted programs that deliver better outcomes sooner. 

With AI-powered prevention and proactive planning, Amadeus AI transforms national health data into national health strategy. 

Amadeus Ai in action

See how leading healthcare organisations are transforming data sharing, care coordination, and outcome.

45 million

Unique patient records safely and securely housed

Malaffi, Abu Dhabi’s state-wide Health Information Exchange, is powered by Orion Health’s Amadeus HIE platform and securely connects over 2,400 facilities and 47,000 users.

By unifying patient data across the emirate, it improves safety, reduces duplication, and streamlines care coordination.

The result? 45 million unique patient records safely housed, enabling better outcomes for patients and providers alike.

10 minutes

To feel confident using the system

Alberta’s EHR initiative breaks down data silos, giving physicians and authorised providers secure, scalable access to critical patient information across the care continuum. The region integrated disparate systems into a single view containing patient lists, demographics, histories, diagnostic reports, and lab results—accessible in real time through an intuitive interface that most clinicians could use after just ten minutes of training.  

The modular, web-based design improved accuracy, reduced delays, and ensured a consistent clinician experience, while preserving existing systems and enabling seamless future upgrades. 

Frequently
Asked Questions

Absolutely. Amadeus AI is a platform that grows with you. If your HIE data isn’t AI-ready today, that’s okay — we’ll work with you to standardise, connect, and enrich it so you’re ready when the time comes.  

In the meantime, Amadeus AI will still improve your clinicians’ workflows by consolidating data into a single, clear view, streamlining referrals, and enhancing care coordination. You’ll see immediate value now, while building the foundation for AI-driven insights in the future. 

Dive deeper in our blog on getting your data AI ready 

Unlike bolt on AI tools, it combines Orion Health’s global HIE experience with native, clinically validated AI transforming data into actionable clarity. 

Amadeus AI has native, embedded intelligence — not bolt-on functionality. It integrates directly into clinical workflows to surface real-time insights, summaries, and predictive recommendations, without disrupting care delivery. 

Amadeus AI is designed to fit seamlessly into complex health IT environments without disruption. It supports HL7 v2, FHIR R4, CDA, and is TEFCA ready, making it fully compatible with US interoperability standards. The platform has proven integrations with major EHR vendors like Epic, Cerner, and Allscripts, ensuring fast deployment and minimal workflow interruption. 

Enterprise grade security certifications including HIPAA, SOC 2, ISO, and HITRUST give health systems confidence whether deploying in the cloud, on premises, or hybrid environments 

Yes. Amadeus is backed by HIPAA, SOC 2, ISO, and HITRUST certifications. Whether deployed in cloud, hybrid, or on premises environments, it maintains enterprise grade security while supporting interoperability and scalability across local, regional, and national infrastructures.

Amadeus AI delivers measurable value across clinical, operational, and financial dimensions: 

  • Reduced duplication and waste – By consolidating siloed data into a single, connected patient record, clinicians avoid repeating tests and procedures, saving both time and cost. 
  • Faster, smarter decisions – Embedded AI tools such as SmartSummary and SmartSearch surface the most relevant information instantly, reducing administrative burden and helping clinicians act with confidence. 
  • Lower operational costs – Event-driven architecture and standards-based interoperability streamline integration, reducing IT maintenance and legacy system costs. 
  • Improved patient outcomes – Predictive analytics and cohort-based care coordination enable earlier interventions, helping populations stay healthier and reducing costly hospital readmissions. 
  • Scalable compliance and resilience – Built to meet TEFCA, CMS 2025, and HIPAA requirements, Amadeus AI helps executives manage risk while confidently scaling from local to national deployments. 


Organisations using Orion Health’s Amadeus platform, from
Malaffi in Abu Dhabi to Alberta Health in Canada, have already demonstrated significant ROI. Millions of patient records have been unified, duplication reduced, and clinical adoption achieved in minutes, not months. 

Yes. Amadeus AI is a modular and flexible platform designed to adapt to the unique needs of different health systems, hospitals, and partners. You can start with core capabilities such as the Clinical Portal or interoperability backbone, and add modules like Care Coordination, Amadeus Insights, or SMARTSuite as your requirements evolve. 

Because it’s standards-based and API-friendly, Amadeus AI integrates smoothly with existing EHRs, HIEs, and third-party applications. Whether you’re a local health network or a national infrastructure, the platform scales with you — ensuring you only invest in what you need, when you need it. 

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